Nucleic Acid Amplification Technologies: Application to Disease Diagnosis (Urban Tapestry Series) - Softcover

Providing current information and guidance on the uses of various nucleic acid amplification technologies for clinical laboratory diagnosis, this book goes beyond PCR to explore a broader range of important alternative DNA/RNA amplification methods including the Ligase Chain Reaction, Q$ Replicase Assays and TMA. There are examples of specific applications, discussions of yet unresolved issues and demonstrations of their relevance to medical research and diagnostics. Individual chapters cover uses in clinical situations -- detection of food pathogens, viral infections, STDs, Mycobacteria drug resistance mutations, and heritable diseases. Automation, diagnostic test evaluation, and synthesis of artificial DNA are also discussed. This book is designed for biomedical scientists interested in applications of molecular biology to clinical diagnosis.