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Mechanisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment (Basic Life Sciences, 38) - Softcover
This book is based on the papers presented at the conference on "Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment," held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired.
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- PublisherSpringer
- Publication date2012
- ISBN 10 1461594642
- ISBN 13 9781461594642
- BindingPaperback
- Number of pages593
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Mechanisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment (Basic Life Sciences) by Simic, Michael G., Upton, Arthur C., Grossman, Lawrence, Bergtold, David S. [Paperback ]
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Mechanisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment (Basic Life Sciences, 38)
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Mechanisms of DNA Damage and Repair
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is based on the papers presented at the conference on 'Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment,' held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired. 596 pp. Englisch. Seller Inventory # 9781461594642
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Mechanisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment
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Book Description Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book is based on the papers presented at the conference on 'Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment,' held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired. Seller Inventory # 9781461594642
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Mechanisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment
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Book Description Paperback. Condition: Brand New. reprint edition. 594 pages. 9.45x6.61x1.35 inches. In Stock. Seller Inventory # x-1461594642
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Book Description Condition: New. Series: Basic Life Sciences. Num Pages: 578 pages, biography. BIC Classification: PNN. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 30. Weight in Grams: 1119. . 2012. Softcover reprint of the original 1st ed. 1986. Paperback. . . . . Seller Inventory # V9781461594642
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